The official website for the Hotel Inhumans television anime has confirmed that voice actor Mitsuki Saiga will join the cast for the series' second season. Saiga is set to portray the character Sekiya, described as a woman frequently observed reading literature regarding murder and poison. This casting announcement follows the earlier additions of Hina Yomiya as Shiba Kirihara and Shōya Chiba as Subaru Yoda. Production for the second season continues under director Tetsuro Amino at studio Bridge, with the studio's subsidiary, Isle, also credited for production. The series retains its core creative team, including series script supervisor Shoji Yonemura, character designer Shingo Fujisaki, sound director Haru Yamada, and composer Koharu. The season's musical themes include the opening track 'Rasen' by GAN and the ending theme 'Sweet Pea' by the group Phantom Siita. The anime, which adapts Ao Tajima's manga series about a luxury hotel catering to professional assassins, debuted its first season in July 2025. The source material concluded its run with the release of the 12th compiled volume in September 2025.